Building on and Integrating Previous Knowledge   - by Ann Burgess Example of a Quiz   - prepared by Lynn Allen-Hoffmann Name ________________________________ Disc. Section ________________________________ Quiz for Week 9 You are on your honor not to discuss this quiz with members of other sections until after 4:30 today. Provide short answers to the following questions: 1. The structure of the BRCA1 protein predicted from its DNA sequence led the authors to speculate that it is a transcription factor. A. Define transcription factor. B. What two structural features of BRCA1 caused them to come to such a conclusion? 2. Once the authors of these papers generated antibodies to BRCA1, list 3 ways they used them to detect the BRCA1 protein. 3. What is the advantage of using a monoclonal antibody rather than polyclonal antisera? 4A. Explain how the subcellular localization of BRCA1 was determined in the 1995 Chen et al. paper. 4B. Where was BRCA1 localized in normal cells? 4C. Where was BRCA1 localized in cell lines established from breast cancer tissue? Tell me more about this plan: A general description Some advice and reflections on this plan Why I like this activity Example of a study guide Example of a quiz Example of a worksheet Example of a team evaluation How much time does this take? More about Ann Burgess

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